TDM is a clinical application for individualizing drug dosage by maintaining plasma or blood drug concentration within a target therapeutic range. Available TDM test assays are summarized in the TDM Test and Pricing Chart.
Tests can be run on a STAT basis, meaning they will be run on the day of receipt if received early enough in the day or not in the normal CPL schedule for that test. Call ahead to facilitate a more rapid turnaround time if necessary. Be sure to mark the appropriate box on the submission form if requesting STAT service. The fee for most STAT testing is $60 for the first test (or peak and trough) on that patient and $30 for subsequent tests on that same sample submission for that patient. The HPLC assay test fee is $200 per assay. STAT fee is added to the cost of monitoring.
For non-human primate sample submission, we are required to follow established protocols in our Biological Use Authorization (BUA) as approved by Auburn University’s Office of Risk Management and Safety. Please review and follow instructions for submitting non-human primate sample(s) before submission of the PRIMATE ONLY TDM submission form (PDF) and corresponding samples.
Due to the cost of required PPE to ensure safe handling of primate samples and the time required to follow the safety protocols outlined in our BUA, a $50 per test (or peak and trough) sample handling fee will be added. If you need assistance with the submission process, please contact the CPL via email or phone as listed in the of this page.
We offer a drug monitoring service for mycophenolate mofetil (MMF) or mycophenolic acid (MPA) in canines and felines. Pricing is $75 for single samples and $120 for both peak and trough samples.
MMF/MPA monitoring is both complicated and limited by the lack of studies correlating concentration and immune suppression in animals. Thus, avoiding toxicity and determining concentrations should be the primary goal. Without consensus regarding MMF therapeutic ranges in animals, establishing the individual patient’s therapeutic range is critical. For more information and sample requirements, click here.
Analytical Chemistry Services consisting of analysis of multiple samples and data (e.g., pharmacokinetic studies, statistical analyses) are offered through the CPL for research projects, which vary from TDM services on clinical patients. We offer development and validation of analytical methods tailored to a particular research project. If you have a project in need of analytical support, contact the pharmacologist and lab manager for more details.
Analytical fees for a new analytical method which include development, validation and data analyses are determined based on a case-by-case basis, based on the complexity of the analysis/project. Pricing varies based on the assay (sample preparation, reagent costs, compound of interest [e.g., parent compound, metabolites, enantiomers], sensitivity) and the number of samples to be analyzed.